Reaction Details
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Report a problem with these dataTarget
Mu-type opioid receptor
Ligand
BDBM50019484
Substrate
n/a
Meas. Tech.
ChEBML_146984
IC50
3.3±n/a nM
Citation
Gairin, JE; Mazarguil, H; Alvinerie, P; Saint-Pierre, S; Meunier, JC; Cros, J Synthesis and biological activities of dynorphin A analogues with opioid antagonist properties. J Med Chem 29:1913-7 (1986) [PubMed] Article More Info.:
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
Inhibitor
Name:
BDBM50019484
Synonyms:
CHEMBL384584 | NH2-Tyr-D-Trp-Gly-Phe-Leu-Arg-Arg-D-Trp-Arg-D-Pro-Lys-OH
Type:
Small organic molecule
Emp. Form.:
C63H103N21O13
Mol. Mass.:
1362.6248
SMILES:
[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@@H]-1-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](-[#8])=O
Structure:
