Target
D(2) dopamine receptor
Ligand
BDBM50019740
Substrate
n/a
Meas. Tech.
ChEMBL_62873 (CHEMBL673584)
Ki
118±n/a nM
Citation
 Abou-Gharbia, MPatel, URMoyer, JAMuth, EA Psychotropic agents: synthesis and antipsychotic activity of substituted beta-carbolines. J Med Chem 30:1100-5 (1987) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50019740
Synonyms:
1-(4-Fluoro-phenyl)-4-[2-(2-pyridin-2-yl-ethyl)-1,2,3,4-tetrahydro-beta-carbolin-9-yl]-butan-1-one | CHEMBL416708
Type:
Small organic molecule
Emp. Form.:
C28H28FN3O
Mol. Mass.:
441.5398
SMILES:
Fc1ccc(cc1)C(=O)CCCn1c2CN(CCc3ccccn3)CCc2c2ccccc12
Structure:
Search PDB for entries with ligand similarity: