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Target
Midkine
Ligand
BDBM50454868
Substrate
n/a
Meas. Tech.
ChEMBL_1753624 (CHEMBL4188384)
IC50
>250000±n/a nM
Citation
 Maza, S; Gandia-Aguado, N; de Paz, JL; Nieto, PM Fluorous-tag assisted synthesis of a glycosaminoglycan mimetic tetrasaccharide as a high-affinity FGF-2 and midkine ligand. Bioorg Med Chem 26:1076-1085 (2018) [PubMed]  Article 
Target
Name:
Midkine
Synonyms:
ARAP | Amphiregulin-associated protein | MDK | MK | MK1 | MK_HUMAN | Midgestation and kidney protein | NEGF2 | Neurite outgrowth-promoting factor 2 | Neurite outgrowth-promoting protein
Type:
PROTEIN
Mol. Mass.:
15605.71
Organism:
Homo sapiens (Human)
Description:
ChEMBL_805023
Residue:
143
Sequence:
MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGTCGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETIRVTKPCTPKTKAKAKAKKGKGKD
  
Inhibitor
Name:
BDBM50454868
Synonyms:
CHEMBL4203669
Type:
Small organic molecule
Emp. Form.:
C21H31NO18S2
Mol. Mass.:
649.597
SMILES:
COc1ccc(O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](COS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2O)cc1 |r|
Structure:
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