Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50455243
Substrate
n/a
Meas. Tech.
ChEMBL_1753998 (CHEMBL4188758)
EC50
40±n/a nM
Citation
 Winters, MP; Sui, Z; Wall, M; Wang, Y; Gunnet, J; Leonard, J; Hua, H; Yan, W; Suckow, A; Bell, A; Clapper, W; Jenkinson, C; Haug, P; Koudriakova, T; Huebert, N; Murray, WV Discovery of N-arylpyrroles as agonists of GPR120 for the treatment of type II diabetes. Bioorg Med Chem Lett 28:841-846 (2018) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50455243
Synonyms:
CHEMBL4212409
Type:
Small organic molecule
Emp. Form.:
C23H20F5NO3
Mol. Mass.:
453.4018
SMILES:
CCc1ccc(cc1)-n1ccc(c1COc1ccc(CCC(O)=O)c(F)c1F)C(F)(F)F
Structure:
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