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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50455365
Substrate
n/a
Meas. Tech.
ChEMBL_1754291 (CHEMBL4189051)
EC50
27±n/a nM
Citation
 Harada, K; Mizukami, J; Kadowaki, S; Matsuda, I; Watanabe, T; Oe, Y; Kodama, Y; Aoki, K; Suwa, K; Fukuda, S; Yata, S; Inaba, T Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure. Bioorg Med Chem Lett 28:1228-1233 (2018) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50455365
Synonyms:
CHEMBL4205711
Type:
Small organic molecule
Emp. Form.:
C25H39NO2
Mol. Mass.:
385.5827
SMILES:
CN(C)C(=O)c1ccc(OCCCCCC2CCC3(CCCCC3)CC2)cc1
Structure:
Search PDB for entries with ligand similarity: