Reaction Details Report a problem with these data
Target
Platelet-activating factor receptor
Ligand
BDBM50021515
Substrate
n/a
Meas. Tech.
ChEBML_151701
IC50
1100±n/a nM
Citation
 Biftu, T; Gamble, NF; Doebber, T; Hwang, SB; Shen, TY; Snyder, J; Springer, JP; Stevenson, R Conformation and activity of tetrahydrofuran lignans and analogues as specific platelet activating factor antagonists. J Med Chem 29:1917-21 (1986) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50021515
Synonyms:
2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan | CHEMBL291515
Type:
Small organic molecule
Emp. Form.:
C22H28O5
Mol. Mass.:
372.4547
SMILES:
COc1ccc(cc1OC)C1O[C@H]([C@@H](C)[C@@H]1C)c1ccc(OC)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: