Reaction Details Report a problem with these data
Target
Kappa-type opioid receptor
Ligand
BDBM50458148
Substrate
n/a
Meas. Tech.
ChEMBL_1762416 (CHEMBL4197663)
Ki
1.3±n/a nM
Citation
 Turnaturi, R; Marrazzo, A; Parenti, C; Pasquinucci, L Benzomorphan scaffold for opioid analgesics and pharmacological tools development: A comprehensive review. Eur J Med Chem 148:410-422 (2018) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa-type opioid receptor | OPRK1
Type:
PROTEIN
Mol. Mass.:
13196.24
Organism:
Macaca mulatta
Description:
ChEMBL_117796
Residue:
115
Sequence:
RYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLR
  
Inhibitor
Name:
BDBM50458148
Synonyms:
CHEMBL4214248
Type:
Small organic molecule
Emp. Form.:
C18H25NO
Mol. Mass.:
271.3972
SMILES:
[H][C@]12Cc3ccc(O)cc3[C@@](C)(CCN1CCC=C)[C@H]2C |r,THB:8:9:19:12.13.14,15:14:19:3.9.2|
Structure:
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