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Target
Cyclin-dependent kinase inhibitor 1
Ligand
BDBM50459994
Substrate
n/a
Meas. Tech.
ChEMBL_1768131 (CHEMBL4220243)
IC50
640±n/a nM
Citation
 Philip, S; Kumarasiri, M; Teo, T; Yu, M; Wang, S Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy? J Med Chem 61:5073-5092 (2018) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase inhibitor 1
Synonyms:
CAP20 | CDK-interacting protein 1 | CDKN1 | CDKN1A | CDN1A_HUMAN | CIP1 | MDA6 | PIC1 | SDI1 | WAF1
Type:
PROTEIN
Mol. Mass.:
18123.15
Organism:
Homo sapiens (Human)
Description:
ChEMBL_312386
Residue:
164
Sequence:
MSEPAGDVRQNPCGSKACRRLFGPVDSEQLSRDCDALMAGCIQEARERWNFDFVTETPLEGDFAWERVRGLGLPKLYLPTGPRRGRDELGGGRRPGTSPALLQGTAEEDHVDLSLSCTLVPRSGEQAEGSPGGPGDSQGRKRRQTSMTDFYHSKRRLIFSKRKP
  
Inhibitor
Name:
BDBM50459994
Synonyms:
CHEMBL4226806 | US11471446, Compound DBA-8
Type:
Small organic molecule
Emp. Form.:
C17H14N4
Mol. Mass.:
274.3199
SMILES:
N#Cc1ccc2ncnc(NCCc3ccccc3)c2c1
Structure:
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