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Target
Opioid receptor delta 1
Ligand
BDBM50268462
Substrate
n/a
Meas. Tech.
ChEMBL_1780615 (CHEMBL4252132)
IC50
2600±n/a nM
Citation
 Helal, MA; Habib, ES; Chittiboyina, AG Selective kappa opioid antagonists for treatment of addiction, are we there yet? Eur J Med Chem 141:632-647 (2017) [PubMed]  Article 
Target
Name:
Opioid receptor delta 1
Synonyms:
G_PROTEIN_RECEP_F1_2 domain-containing protein | OPRD1
Type:
PROTEIN
Mol. Mass.:
40087.02
Organism:
Cavia porcellus
Description:
ChEMBL_117772
Residue:
366
Sequence:
MEPAPSAGAELQPSFLPNASDAYPSTFPSAGANASGPPGTRSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRHDPFVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRSPCGRPEPSSFSRAREATARERVTACTPSDGP
  
Inhibitor
Name:
BDBM50268462
Synonyms:
CHEMBL506616 | c[L-Phe-D-pro-L-Phe-L-trp]
Type:
Small organic molecule
Emp. Form.:
C34H35N5O4
Mol. Mass.:
577.6728
SMILES:
O=C1N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N2CCC[C@H]12 |r|
Structure:
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