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Target
Structural capsid protein
Ligand
BDBM50467393
Substrate
n/a
Meas. Tech.
ChEMBL_1795991 (CHEMBL4268108)
Kd
11000±n/a nM
Citation
 Wu, G; Zalloum, WA; Meuser, ME; Jing, L; Kang, D; Chen, CH; Tian, Y; Zhang, F; Cocklin, S; Lee, KH; Liu, X; Zhan, P Discovery of phenylalanine derivatives as potent HIV-1 capsid inhibitors from click chemistry-based compound library. Eur J Med Chem 158:478-492 (2018) [PubMed]  Article 
Target
Name:
Structural capsid protein
Synonyms:
Structural capsid protein | gag
Type:
PROTEIN
Mol. Mass.:
12762.23
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_106648
Residue:
115
Sequence:
ELERFAVNPALLETSEGCRQILGQLQPSLQTGSEELKSLFNTVATLYCVHQRIEVKDTKEALDKIEEEQNKSKKKAQQAQQAAAATGSSQVSQNYPIVQNLQGQMVHQPISPRTL
  
Inhibitor
Name:
BDBM50467393
Synonyms:
CHEMBL4278296
Type:
Small organic molecule
Emp. Form.:
C31H29N5O3
Mol. Mass.:
519.5937
SMILES:
COc1ccc(cc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)c1cn(Cc2ccc3ccccc3c2)nn1 |r|
Structure:
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