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Target
Sensor protein kinase WalK
Ligand
BDBM50368125
Substrate
n/a
Meas. Tech.
ChEMBL_1799291 (CHEMBL4271583)
IC50
7189±n/a nM
Citation
 Wilke, KE; Fihn, CA; Carlson, EE Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition. Bioorg Med Chem 26:5322-5326 (2018) [PubMed]  Article 
Target
Name:
Sensor protein kinase WalK
Synonyms:
2.7.13.3 | Sensor protein kinase WalK | WALK_STAAU | vicK | walK | yycG
Type:
PROTEIN
Mol. Mass.:
47805.74
Organism:
Staphylococcus aureus
Description:
ChEMBL_118213
Residue:
415
Sequence:
CTVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE
  
Inhibitor
Name:
BDBM50368125
Synonyms:
ADENOSINE DIPHOSPHATE | ADP
Type:
Small organic molecule
Emp. Form.:
C10H15N5O10P2
Mol. Mass.:
427.2011
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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