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Target
Sensor protein kinase WalK
Ligand
BDBM153747
Substrate
n/a
Meas. Tech.
ChEMBL_1799291 (CHEMBL4271583)
IC50
883300000±n/a nM
Citation
 Wilke, KE; Fihn, CA; Carlson, EE Screening serine/threonine and tyrosine kinase inhibitors for histidine kinase inhibition. Bioorg Med Chem 26:5322-5326 (2018) [PubMed]  Article 
Target
Name:
Sensor protein kinase WalK
Synonyms:
2.7.13.3 | Sensor protein kinase WalK | WALK_STAAU | vicK | walK | yycG
Type:
PROTEIN
Mol. Mass.:
47805.74
Organism:
Staphylococcus aureus
Description:
ChEMBL_118213
Residue:
415
Sequence:
CTVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE
  
Inhibitor
Name:
BDBM153747
Synonyms:
ROCHE screening, 65
Type:
Small organic molecule
Emp. Form.:
C14H11N3O2S
Mol. Mass.:
285.321
SMILES:
CONC1=NC(=O)\C(S1)=C\c1ccc2ncccc2c1 |t:3|
Structure:
Search PDB for entries with ligand similarity: