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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50026385
Substrate
n/a
Meas. Tech.
ChEMBL_201212 (CHEMBL804008)
Ki
67±n/a nM
Citation
 Huff, JR; King, SW; Saari, WS; Springer, JP; Martin, GE; Williams, M Bioactive conformation of 1-arylpiperazines at central serotonin receptors. J Med Chem 28:945-8 (1985) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50026385
Synonyms:
9-Trifluoromethyl-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline | CHEMBL351530
Type:
Small organic molecule
Emp. Form.:
C13H15F3N2
Mol. Mass.:
256.2668
SMILES:
FC(F)(F)c1ccc2CCC3CNCCN3c2c1
Structure:
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