Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50473388
Substrate
n/a
Meas. Tech.
ChEMBL_105112 (CHEMBL715955)
Ki
275±n/a nM
Citation
 Spadoni, G; Balsamini, C; Diamantini, G; Tontini, A; Tarzia, G; Mor, M; Rivara, S; Plazzi, PV; Nonno, R; Lucini, V; Pannacci, M; Fraschini, F; Stankov, BM 2-N-acylaminoalkylindoles: design and quantitative structure-activity relationship studies leading to MT2-selective melatonin antagonists. J Med Chem 44:2900-12 (2001) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50473388
Synonyms:
CHEMBL98956
Type:
Small organic molecule
Emp. Form.:
C13H15BrN2O2
Mol. Mass.:
311.174
SMILES:
CCC(=O)NCc1[nH]c2cc(OC)ccc2c1Br
Structure:
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