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Target
Mu-type opioid receptor
Ligand
BDBM50474329
Substrate
n/a
Meas. Tech.
ChEMBL_148364 (CHEMBL857863)
Ki
87±n/a nM
Citation
 Kolczewski, S; Adam, G; Cesura, AM; Jenck, F; Hennig, M; Oberhauser, T; Poli, SM; Rössler, F; Röver, S; Wichmann, J; Dautzenberg, FM Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists. J Med Chem 46:255-64 (2003) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50474329
Synonyms:
CHEMBL315551
Type:
Small organic molecule
Emp. Form.:
C27H43N3
Mol. Mass.:
409.6504
SMILES:
[H][C@]12CN(C)C[C@@]1([H])C1(CCN(CC1)C1CCCCCCCCC1)N(C2)c1ccccc1
Structure:
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