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Target
Transporter
Ligand
BDBM76298
Substrate
n/a
Meas. Tech.
ChEBML_129897
IC50
>34000±n/a nM
Citation
 Högberg, T; Ulff, B; Renyi, AL; Ross, SB Synthesis of pyridylallylamines related to zimelidine and their inhibition of neuronal monoamine uptake. J Med Chem 24:1499-507 (1982) [PubMed]  Article 
Target
Name:
Transporter
Synonyms:
Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters
Type:
PROTEIN
Mol. Mass.:
66787.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1463061
Residue:
597
Sequence:
MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
  
Inhibitor
Name:
BDBM76298
Synonyms:
2-aminopropanoic acid [1-(4-chlorophenyl)-2-methylpropan-2-yl] ester;hydrochloride | 2-aminopropionic acid [2-(4-chlorophenyl)-1,1-dimethyl-ethyl] ester;hydrochloride | ALAPROCLATE HYDROCHLORIDE | Alaproclate | CHEMBL36591 | MLS002153522 | SMR001230852 | [1-(4-chlorophenyl)-2-methyl-propan-2-yl] 2-azanylpropanoate;hydrochloride | [1-(4-chlorophenyl)-2-methylpropan-2-yl] 2-aminopropanoate;hydrochloride | cid_11957454
Type:
Small organic molecule
Emp. Form.:
C13H18ClNO2
Mol. Mass.:
255.741
SMILES:
CC(N)C(=O)OC(C)(C)Cc1ccc(Cl)cc1
Structure:
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