Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50476626
Substrate
n/a
Meas. Tech.
ChEMBL_444318 (CHEMBL894558)
Ki
1.8±n/a nM
Citation
 Faust, R; Garratt, PJ; Trujillo Pérez, MA; Piccio, VJ; Madsen, C; Stenstrĝm, A; Frĝlund, B; Davidson, K; Teh, MT; Sugden, D 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: effect of substituents on potency and binding affinity. Bioorg Med Chem 15:4543-51 (2007) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50476626
Synonyms:
CHEMBL395221
Type:
Small organic molecule
Emp. Form.:
C15H20N2O2
Mol. Mass.:
260.3315
SMILES:
CCC(=O)NCCc1c[nH]c2c(C)cc(OC)cc12
Structure:
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