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Target
Beta-2 adrenergic receptor
Ligand
BDBM50477621
Substrate
n/a
Meas. Tech.
ChEMBL_456464 (CHEMBL887285)
EC50
100±n/a nM
Citation
 Shearer, BG; Chao, EY; Uehling, DE; Deaton, DN; Cowan, C; Sherman, BW; Milliken, T; Faison, W; Brown, K; Adkison, KK; Lee, F Synthesis and evaluation of potent and selective beta3 adrenergic receptor agonists containing heterobiaryl carboxylic acids. Bioorg Med Chem Lett 17:4670-7 (2007) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50477621
Synonyms:
CHEMBL393470
Type:
Small organic molecule
Emp. Form.:
C21H22ClN3O3S
Mol. Mass.:
431.936
SMILES:
C[C@H](CNc1cccc(c1)-c1csc(n1)C(O)=O)NC[C@H](O)c1cccc(Cl)c1
Structure:
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