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Target
Reverse transcriptase protein
Ligand
BDBM5056
Substrate
n/a
Meas. Tech.
ChEMBL_465974 (CHEMBL947217)
IC50
6918±n/a nM
Citation
 San Juan, AA 3D-QSAR models on clinically relevant K103N mutant HIV-1 reverse transcriptase obtained from two strategic considerations. Bioorg Med Chem Lett 18:1181-94 (2008) [PubMed]  Article 
Target
Name:
Reverse transcriptase protein
Synonyms:
Reverse Transcriptase | Reverse Transcriptase (A62V) | Reverse Transcriptase (F61A)
Type:
Protein
Mol. Mass.:
30203.56
Organism:
Human immunodeficiency virus 1
Description:
Q9WJQ2
Residue:
259
Sequence:
PISPIEPVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYEHHPDKWTVQPIVLPEKDSWTVNDIQK
  
Inhibitor
Name:
BDBM5056
Synonyms:
N-[(2Z)-4-chloro-3-methyl-5-(propan-2-yl)-2,3-dihydro-1,3-thiazol-2-ylidene]-3-nitrobenzene-1-sulfonamide | thiazolidenebenzenesulfonamide deriv. 17k | thiazolidenebenzenesulfonamide deriv. 2
Type:
Small organic molecule
Emp. Form.:
C13H14ClN3O4S2
Mol. Mass.:
375.851
SMILES:
CC(C)c1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1Cl
Structure:
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