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Target
Reverse transcriptase
Ligand
BDBM1751
Substrate
n/a
Meas. Tech.
ChEMBL_545024 (CHEMBL1016320)
IC50
119950±n/a nM
Citation
 Hu, R; Doucet, JP; Delamar, M; Zhang, R QSAR models for 2-amino-6-arylsulfonylbenzonitriles and congeners HIV-1 reverse transcriptase inhibitors based on linear and nonlinear regression methods. Eur J Med Chem 44:2158-71 (2009) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM1751
Synonyms:
2-Amino-6-arylthiobenzonitrile deriv. 1u | 2-amino-6-[(3,5-dichlorophenyl)sulfanyl]benzonitrile
Type:
Small organic molecule
Emp. Form.:
C13H8Cl2N2S
Mol. Mass.:
295.187
SMILES:
Nc1cccc(Sc2cc(Cl)cc(Cl)c2)c1C#N
Structure:
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