Reaction Details Report a problem with these data
Target
Platelet glycoprotein 4
Ligand
BDBM50483629
Substrate
n/a
Meas. Tech.
ChEMBL_740315 (CHEMBL1764261)
IC50
2280±n/a nM
Citation
 Wang, YX; Wang, L; Xu, YN; Li, YH; Jiang, JD; Si, SY; Li, YB; Ren, G; Shan, YQ; Hong, B; Song, DQ Synthesis and structure-activity relationship of N-(2-arylethyl) isoquinoline derivatives as human scavenger receptor CD36 antagonists. Eur J Med Chem 46:1066-73 (2011) [PubMed]  Article 
Target
Name:
Platelet glycoprotein 4
Synonyms:
CD36 | CD36_HUMAN | CD_antigen=CD36 | FAT | Fatty acid translocase | GP3B | GP4 | GPIIIB | GPIV | Glycoprotein IIIb | Leukocyte differentiation antigen CD36 | PAS IV | PAS-4 | Platelet collagen receptor | Platelet glycoprotein 4 | Platelet glycoprotein IV | Thrombospondin receptor
Type:
PROTEIN
Mol. Mass.:
53057.78
Organism:
Homo sapiens
Description:
ChEMBL_104107
Residue:
472
Sequence:
MGCDRNCGLIAGAVIGAVLAVFGGILMPVGDLLIQKTIKKQVVLEEGTIAFKNWVKTGTEVYRQFWIFDVQNPQEVMMNSSNIQVKQRGPYTYRVRFLAKENVTQDAEDNTVSFLQPNGAIFEPSLSVGTEADNFTVLNLAVAAASHIYQNQFVQMILNSLINKSKSSMFQVRTLRELLWGYRDPFLSLVPYPVTTTVGLFYPYNNTADGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESHCDMINGTDAASFPPFVEKSQVLQFFSSDICRSIYAVFESDVNLKGIPVYRFVLPSKAFASPVENPDNYCFCTEKIISKNCTSYGVLDISKCKEGRPVYISLPHFLYASPDVSEPIDGLNPNEEEHRTYLDIEPITGFTLQFAKRLQVNLLVKPSEKIQVLKNLKRNYIVPILWLNETGTIGDEKANMFRSQVTGKINLLGLIEMILLSVGVVMFVAFMISYCACRSKTIK
  
Inhibitor
Name:
BDBM50483629
Synonyms:
CHEMBL1761171
Type:
Small organic molecule
Emp. Form.:
C18H17Cl2NO2
Mol. Mass.:
350.239
SMILES:
[Cl-].COc1cc2c[n+](CCc3cccc(Cl)c3)ccc2cc1O
Structure:
Search PDB for entries with ligand similarity: