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Target
Potassium voltage-gated channel subfamily A member 3
Ligand
BDBM50030521
Substrate
n/a
Meas. Tech.
ChEMBL_141442 (CHEMBL750215)
IC50
164±n/a nM
Citation
 Michne, WF; Guiles, JW; Treasurywala, AM; Castonguay, LA; Weigelt, CA; Oconnor, B; Volberg, WA; Grant, AM; Chadwick, CC; Krafte, DS Novel inhibitors of potassium ion channels on human T lymphocytes. J Med Chem 38:1877-83 (1995) [PubMed]  Article 
Target
Name:
Potassium voltage-gated channel subfamily A member 3
Synonyms:
HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3
Type:
PROTEIN
Mol. Mass.:
63835.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1513935
Residue:
575
Sequence:
MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
  
Inhibitor
Name:
BDBM50030521
Synonyms:
CHEMBL56173 | [1-Benzyl-1H-quinolin-(4E)-ylidene]-hexyl-amine
Type:
Small organic molecule
Emp. Form.:
C22H26N2
Mol. Mass.:
318.4552
SMILES:
CCCCCC\N=c1/ccn(Cc2ccccc2)c2ccccc12
Structure:
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