Reaction Details Report a problem with these data
Target
Carbonic anhydrase 4
Ligand
BDBM50515806
Substrate
n/a
Meas. Tech.
ChEMBL_1969935 (CHEMBL4602753)
IC50
21±n/a nM
Citation
 Zhao, C; Rakesh, KP; Ravidar, L; Fang, WY; Qin, HL Pharmaceutical and medicinal significance of sulfur (S Eur J Med Chem 162:679-734 (2019) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Homo sapiens (Human)
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM50515806
Synonyms:
CHEMBL4533252
Type:
Small organic molecule
Emp. Form.:
C18H19N3O5S
Mol. Mass.:
389.426
SMILES:
COc1ccc(cc1)C1=NN(C(C1)c1ccc(OS(N)(=O)=O)cc1)C(C)=O |t:9|
Structure:
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