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Target
Type-1 angiotensin II receptor
Ligand
BDBM50005347
Substrate
n/a
Meas. Tech.
ChEMBL_910709 (CHEMBL3056264)
IC50
1100±n/a nM
Citation
  TBA Med Chem Res 19:177-185 (2010)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_BOVIN | Angiotensin II type 1a (AT-1a) receptor
Type:
PROTEIN
Mol. Mass.:
41107.81
Organism:
Bos taurus
Description:
ChEMBL_36779
Residue:
359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFIMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPTIIHRNVFFIENTNITVCAFHYESQNSTLPVGLGLTKNILGFLFPFLIILTSYTLIWKTLKKAYEIQKNKPRKDDIFKIILAIVLFFFFSWVPHQIFTFMDVLIQLGLIRDCKIEDIVDTAMPITICLAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSENGNSSTKKPAPCIEVE
  
Inhibitor
Name:
BDBM50005347
Synonyms:
4'-((2-butyl-1H-benzo[d]imidazol-1-yl)methyl)biphenyl-2-carboxylic acid | 4'-(2-Butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid | 4'-(2-Butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid;0.25H2O | CHEMBL7632
Type:
Small organic molecule
Emp. Form.:
C25H24N2O2
Mol. Mass.:
384.4703
SMILES:
CCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Structure:
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