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Target
Nicotinic acetylcholine receptor alpha 5 subunit
Ligand
BDBM50488014
Substrate
n/a
Meas. Tech.
ChEMBL_916292 (CHEMBL3081150)
Ki
6.0±n/a nM
Citation
 Samaritoni, JG; Demeter, DA; Gifford, JM; Watson, GB; Kempe, MS; Bruce, TJ Dihydropiperazine neonicotinoid compounds. Synthesis and insecticidal activity. J Agric Food Chem 51:3035-42 (2003) [PubMed]  Article 
Target
Name:
Nicotinic acetylcholine receptor alpha 5 subunit
Synonyms:
Nicotinic acetylcholine receptor alpha 5 subunit | nAChRalpha5
Type:
PROTEIN
Mol. Mass.:
88489.00
Organism:
Musca domestica
Description:
ChEMBL_106552
Residue:
781
Sequence:
MMWEMLILWAVHLSLTAIATLYANVRTALSQTAQQIVRAVIAATTLPIIQRIQQQQHETEKQQQQLQHGKHVEDIHLPAAGARYASASSSRLPPSSADATIWPRAPPELPQTEKLSSAPPPPSSSSTLLMQTKPAHKKPVHGRNFPPQQKNRMQPVSHLQYQQQQQQQLSLPSPAEPQPQHYKQQQQQQGQERLGQQVNINNITSSSNGGNTCSSNSFTATTSIAATTTTSILTLWQHCHRRYRPHQLLPLLTTKGLNKYSWIFLLIYLNLSAKVCLAGYNEKRLLHDLLDTYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGIKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRVVFLCWLPWILRMHRPGRPIIMDFTSTPCSDTSSERKHQILSDVELKERSSKSLLANVLDIDDDFRNVRPMTPGGTLPHNPAFYRTVYGYLENLQGDDGSIGPIGSTRMPDAVTHHTCIKTQTEYELSLILKEIRFITDQLRKEDEENGIANDWKFAAMVVDRLCLIIFTMFAILATIAVLLSAPHVIVS
  
Inhibitor
Name:
BDBM50488014
Synonyms:
CHEMBL2272690
Type:
Small organic molecule
Emp. Form.:
C12H12ClN5O
Mol. Mass.:
277.71
SMILES:
CN1CCN(Cc2ccc(Cl)nc2)\C(=N\C#N)C1=O
Structure:
Search PDB for entries with ligand similarity: