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Target
Transcription factor 7-like 2
Ligand
BDBM50094484
Substrate
n/a
Meas. Tech.
ChEMBL_938104 (CHEMBL2328064)
Ki
5900±n/a nM
Citation
 Zhang, M; Catrow, JL; Ji, H High-Throughput Selectivity Assays for Small-Molecule Inhibitors of ?-Catenin/T-Cell Factor Protein-Protein Interactions. ACS Med Chem Lett 4:306-11 (2013) [PubMed]  Article 
Target
Name:
Transcription factor 7-like 2
Synonyms:
HMG box transcription factor 4 | T-cell factor 4 | T-cell-specific transcription factor 4 | TCF-4 | TCF4 | TCF7L2 | TF7L2_HUMAN | hTCF-4
Type:
PROTEIN
Mol. Mass.:
67939.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_107937
Residue:
619
Sequence:
MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPCRRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKPDPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSHSSLAGTQPQPLSLVTKSLE
  
Inhibitor
Name:
BDBM50094484
Synonyms:
CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 | US9738628, Compound CGP049090
Type:
Small organic molecule
Emp. Form.:
C29H26O10
Mol. Mass.:
534.5107
SMILES:
COc1c(C[C@H](C)O)c2c3c(C[C@H](C)O)c(OC)c(=O)c4c(O)cc5OCOc6cc(O)c(c2c6c5c34)c1=O |r|
Structure:
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