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Target
Delta-type opioid receptor
Ligand
BDBM50492487
Substrate
n/a
Meas. Tech.
ChEMBL_969753 (CHEMBL2404095)
Ki
11±n/a nM
Citation
 Touati-Jallabe, Y; Bojnik, E; Legrand, B; Mauchauffée, E; Chung, NN; Schiller, PW; Benyhe, S; Averlant-Petit, MC; Martinez, J; Hernandez, JF Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations. J Med Chem 56:5964-5973 (2013) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50492487
Synonyms:
CHEMBL2402937
Type:
Small organic molecule
Emp. Form.:
C28H36N8O6S
Mol. Mass.:
612.7
SMILES:
CS\C1=N\C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CN1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O |r,t:2|
Structure:
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