Reaction Details Report a problem with these data
Target
Reverse transcriptase
Ligand
BDBM1751
Substrate
n/a
Meas. Tech.
ChEMBL_985351 (CHEMBL2432160)
IC50
120±n/a nM
Citation
  TBA Med Chem Res 0:1-11 (2013)    Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM1751
Synonyms:
2-Amino-6-arylthiobenzonitrile deriv. 1u | 2-amino-6-[(3,5-dichlorophenyl)sulfanyl]benzonitrile
Type:
Small organic molecule
Emp. Form.:
C13H8Cl2N2S
Mol. Mass.:
295.187
SMILES:
Nc1cccc(Sc2cc(Cl)cc(Cl)c2)c1C#N
Structure:
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