Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM26664
Substrate
n/a
Meas. Tech.
ChEMBL_31065 (CHEMBL641349)
Ki
2680±n/a nM
Citation
 Ji, XD; Melman, N; Jacobson, KA Interactions of flavonoids and other phytochemicals with adenosine receptors. J Med Chem 39:781-8 (1996) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rattus norvegicus (rat)
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM26664
Synonyms:
7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-hydroxy-2-phenyl-4H-chromen-4-one | 7-hydroxyflavone | CHEMBL276915
Type:
Flavonoid
Emp. Form.:
C15H10O3
Mol. Mass.:
238.2381
SMILES:
Oc1ccc2c(c1)oc(cc2=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: