Reaction Details Report a problem with these data
Target
Integrase
Ligand
BDBM50057353
Substrate
n/a
Meas. Tech.
ChEMBL_90715 (CHEMBL702114)
IC50
>350000±n/a nM
Citation
 Zhao, H; Neamati, N; Mazumder, A; Sunder, S; Pommier, Y; Burke, TR Arylamide inhibitors of HIV-1 integrase. J Med Chem 40:1186-94 (1997) [PubMed]  Article 
Target
Name:
Integrase
Synonyms:
Human immunodeficiency virus type 1 integrase
Type:
PROTEIN
Mol. Mass.:
32231.48
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_90865
Residue:
288
Sequence:
FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
  
Inhibitor
Name:
BDBM50057353
Synonyms:
3-(3,5-Dihydroxy-phenyl)-N-[2-(3,4-dihydroxy-phenyl)-ethyl]-propionamide | CHEMBL428345
Type:
Small organic molecule
Emp. Form.:
C17H19NO5
Mol. Mass.:
317.3365
SMILES:
Oc1cc(O)cc(CCC(=O)NCCc2ccc(O)c(O)c2)c1
Structure:
Search PDB for entries with ligand similarity: