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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50281388
Substrate
n/a
Meas. Tech.
ChEMBL_1829182 (CHEMBL4329056)
IC50
78±n/a nM
Citation
 ?a?ewska, D; Olejarz-Maciej, A; Kaleta, M; Bajda, M; Siwek, A; Karcz, T; Doroz-P?onka, A; Cicho?, U; Kuder, K; Kie?-Kononowicz, K 4-tert-Pentylphenoxyalkyl derivatives - Histamine H Bioorg Med Chem Lett 28:3596-3600 (2018) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50281388
Synonyms:
CHEMBL4173258
Type:
Small organic molecule
Emp. Form.:
C22H31N3O
Mol. Mass.:
353.501
SMILES:
CN(CC#C)Cc1cc2cc(OCCCN3CCCCC3)ccc2n1C
Structure:
Search PDB for entries with ligand similarity: