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Target
Cathepsin G
Ligand
BDBM50060332
Substrate
n/a
Meas. Tech.
ChEMBL_45530 (CHEMBL660233)
pH
7.5±n/a
Ki
>15000±n/a nM
Comments
extracted
Citation
 Regan, J; McGarry, D; Bruno, J; Green, D; Newman, J; Hsu, CY; Kline, J; Barton, J; Travis, J; Choi, YM; Volz, F; Pauls, H; Harrison, R; Zilberstein, A; Ben-Sasson, SA; Chang, M Anionic- and lipophilic-mediated surface binding inhibitors of human leukocyte elastase. J Med Chem 40:3408-22 (1997) [PubMed]  Article 
Target
Name:
Cathepsin G
Synonyms:
CATG_HUMAN | CG | CTSG
Type:
PROTEIN
Mol. Mass.:
28860.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469016
Residue:
255
Sequence:
MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYDPRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRTTMRSFKLLDQMETPL
  
Inhibitor
Name:
BDBM50060332
Synonyms:
CHEMBL215927
Type:
Small organic molecule
Emp. Form.:
C66H80O24
Mol. Mass.:
1257.327
SMILES:
COCCOCOc1cc(Cc2cc(OC)c(Cc3cc(OC)c(Cc4cc(OC)c(Cc5cc(OC)c(Cc6cc(OC)ccc6OCC(O)=O)cc5OCOCCOC)cc4OCC(O)=O)cc3OCOCCOC)cc2OCC(O)=O)c(OC)cc1C
Structure:
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