Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50061324
Substrate
n/a
Meas. Tech.
ChEMBL_60064 (CHEMBL671378)
Ki
296±n/a nM
Citation
 Unangst, PC; Capiris, T; Connor, DT; Doubleday, R; Heffner, TG; MacKenzie, RG; Miller, SR; Pugsley, TA; Wise, LD (Aryloxy)alkylamines as selective human dopamine D4 receptor antagonists: potential antipsychotic agents. J Med Chem 40:4026-9 (1998) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50061324
Synonyms:
(2-p-Tolyloxy-ethyl)-(3-o-tolyloxy-propyl)-amine | CHEMBL334545
Type:
Small organic molecule
Emp. Form.:
C19H25NO2
Mol. Mass.:
299.4073
SMILES:
Cc1ccc(OCCNCCCOc2ccccc2C)cc1
Structure:
Search PDB for entries with ligand similarity: