Reaction Details Report a problem with these data
Target
Casein kinase II subunit alpha
Ligand
BDBM50508987
Substrate
n/a
Meas. Tech.
ChEMBL_1836632 (CHEMBL4336765)
Ki
7.0±n/a nM
Citation
 Qiao, Y; Chen, T; Yang, H; Chen, Y; Lin, H; Qu, W; Feng, F; Liu, W; Guo, Q; Liu, Z; Sun, H Small molecule modulators targeting protein kinase CK1 and CK2. Eur J Med Chem 181:0 (2019) [PubMed]  Article 
Target
Name:
Casein kinase II subunit alpha
Synonyms:
CK II | CK2 | CK2- alpha | CK2A1 | CSK21_HUMAN | CSNK2A1 | Casein kinase 2 | Casein kinase II (CK2) | Casein kinase II alpha/beta | Casein kinase II subunit alpha (CK2 alpha) | Casein kinase II subunit alpha (CK2A1) | Casein kinase II subunit alpha (CK2a I174A) | Casein kinase II subunit alpha (CK2a V66A) | Casein kinase II subunit alpha (CK2a dm V66I174AA) | Casein kinase II subunit alpha (CK2a)
Type:
Enzyme
Mol. Mass.:
45151.12
Organism:
Homo sapiens (Human)
Description:
P68400
Residue:
391
Sequence:
MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
  
Inhibitor
Name:
BDBM50508987
Synonyms:
CHEMBL4465651
Type:
Small organic molecule
Emp. Form.:
C13H7BrO4
Mol. Mass.:
307.096
SMILES:
Oc1ccc2c3ccc(O)c(Br)c3oc(=O)c2c1
Structure:
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