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Target
Chymotrypsinogen A
Ligand
BDBM50065899
Substrate
n/a
Meas. Tech.
ChEMBL_34105 (CHEMBL649734)
IC50
2200±n/a nM
Citation
 Yoakim, C; Ogilvie, WW; Cameron, DR; Chabot, C; Guse, I; Haché, B; Naud, J; O'Meara, JA; Plante, R; Déziel, R beta-Lactam derivatives as inhibitors of human cytomegalovirus protease. J Med Chem 41:2882-91 (1998) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50065899
Synonyms:
(2S,3S)-2-Benzyl-3-methylsulfanyl-4-oxo-azetidine-1-carboxylic acid (pyridin-4-ylmethyl)-amide | CHEMBL95260
Type:
Small organic molecule
Emp. Form.:
C18H19N3O2S
Mol. Mass.:
341.427
SMILES:
CS[C@H]1[C@H](Cc2ccccc2)N(C(=O)NCc2ccncc2)C1=O
Structure:
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