Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50067096
Substrate
n/a
Meas. Tech.
ChEMBL_29466 (CHEMBL642195)
Ki
3200000±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Link, R; van der Goot, H; Ijzerman, AP A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem 41:3994-4000 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50067096
Synonyms:
CHEMBL71053 | N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-benzamide | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-benzamide(VUF8507) | VUF-8507
Type:
Small organic molecule
Emp. Form.:
C21H15N3O
Mol. Mass.:
325.3633
SMILES:
O=C(Nc1nc(cc2ccccc12)-c1ccccn1)c1ccccc1
Structure:
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