Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50067089
Substrate
n/a
Meas. Tech.
ChEMBL_31996 (CHEMBL646593)
Ki
740000±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Link, R; van der Goot, H; Ijzerman, AP A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem 41:3994-4000 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50067089
Synonyms:
CHEMBL72897 | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-benzamidine
Type:
Small organic molecule
Emp. Form.:
C21H16N4
Mol. Mass.:
324.3785
SMILES:
NC(=Nc1nc(cc2ccccc12)-c1ccccn1)c1ccccc1 |w:2.2|
Structure:
Search PDB for entries with ligand similarity: