Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50067115
Substrate
n/a
Meas. Tech.
ChEMBL_31995 (CHEMBL646592)
Ki
48000000±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Link, R; van der Goot, H; Ijzerman, AP A novel class of adenosine A3 receptor ligands. 2. Structure affinity profile of a series of isoquinoline and quinazoline compounds. J Med Chem 41:3994-4000 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50067115
Synonyms:
CHEMBL335744 | N-(3-Pyridin-2-yl-isoquinolin-1-yl)-isobutyramide
Type:
Small organic molecule
Emp. Form.:
C18H17N3O
Mol. Mass.:
291.3471
SMILES:
CC(C)C(=O)Nc1nc(cc2ccccc12)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: