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Target
P2Y purinoceptor 14
Ligand
BDBM50343888
Substrate
n/a
Meas. Tech.
ChEMBL_1848890 (CHEMBL4349431)
Ki
4.0±n/a nM
Citation
 Lu, R; Zhang, Z; Jiang, C Recent progress on the discovery of P2Y Eur J Med Chem 175:34-39 (2019) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
G-protein coupled receptor 105 | Gpr105 | P2Y14 | P2Y14_MOUSE | P2ry14 | UDP-glucose receptor
Type:
PROTEIN
Mol. Mass.:
38883.93
Organism:
Mus musculus
Description:
ChEMBL_745158
Residue:
338
Sequence:
MNNSTTTDPPNQPCSWNTLITKQIIPVLYGMVFITGLLLNGISGWIFFYVPSSKSFIIYLKNIVVADFLMGLTFPFKVLGDSGLGPWQVNVFVCRVSAVIFYVNMYVSIVFFGLISFDRYYKIVKPLLTSIVQSVNYSKLLSVLVWMLMLLLAVPNIILTNQGVKEVTKIQCMELKNELGRKWHKASNYIFVSIFWVVFLLLIVFYTAITRKIFKSHLKSRKNSTSVKRKSSRNIFSIVLVFVVCFVPYHIARIPYTKSQTEGHYSCRTKETLLYAKEFTLLLSAANVCLDPIIYFFLCQPFREVLNKKLHMSLKVQNDLEVSKTKRENAIHESTDTL
  
Inhibitor
Name:
BDBM50343888
Synonyms:
(R)-4-(4-(2,2-difluoro-1-hydroxyethyl)phenyl)-7-(4-(trifluoromethyl)phenyl)-2-naphthoic acid | CHEMBL1774903
Type:
Small organic molecule
Emp. Form.:
C26H17F5O3
Mol. Mass.:
472.4034
SMILES:
O[C@@H](C(F)F)c1ccc(cc1)-c1cc(cc2cc(ccc12)-c1ccc(cc1)C(F)(F)F)C(O)=O |r|
Structure:
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