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Target
Potassium voltage-gated channel subfamily C member 1
Ligand
BDBM50067878
Substrate
n/a
Meas. Tech.
ChEMBL_92814 (CHEMBL702910)
Kd
29000±n/a nM
Citation
 Wulff, H; Rauer, H; Düring, T; Hanselmann, C; Ruff, K; Wrisch, A; Grissmer, S; Hänsel, W Alkoxypsoralens, novel nonpeptide blockers of Shaker-type K+ channels: synthesis and photoreactivity. J Med Chem 41:4542-9 (1998) [PubMed]  Article 
Target
Name:
Potassium voltage-gated channel subfamily C member 1
Synonyms:
KCNC1 | KCNC1_HUMAN | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv3.1
Type:
PROTEIN
Mol. Mass.:
57942.24
Organism:
Homo sapiens (Human)
Description:
ChEMBL_92814
Residue:
511
Sequence:
MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI
  
Inhibitor
Name:
BDBM50067878
Synonyms:
9-Methoxy-furo[3',2':4,5]benzo[1,2-b][1,4]oxazin-3-one | CHEMBL141623
Type:
Small organic molecule
Emp. Form.:
C11H7NO4
Mol. Mass.:
217.1776
SMILES:
COc1c2ccoc2cc2oc(=O)cnc12
Structure:
Search PDB for entries with ligand similarity: