Reaction Details
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Potassium voltage-gated channel subfamily C member 1
Ligand
BDBM50067879
Substrate
n/a
Meas. Tech.
ChEMBL_92814 (CHEMBL702910)
Kd
213000±n/a nM
Citation
Wulff, H; Rauer, H; Düring, T; Hanselmann, C; Ruff, K; Wrisch, A; Grissmer, S; Hänsel, W Alkoxypsoralens, novel nonpeptide blockers of Shaker-type K+ channels: synthesis and photoreactivity. J Med Chem 41:4542-9 (1998) [PubMed] Article More Info.:
Target
Name:
Potassium voltage-gated channel subfamily C member 1
Synonyms:
KCNC1 | KCNC1_HUMAN | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv3.1
Type:
PROTEIN
Mol. Mass.:
57942.24
Organism:
Homo sapiens (Human)
Description:
ChEMBL_92814
Residue:
511
Sequence:
MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI
Inhibitor
Name:
BDBM50067879
Synonyms:
5-Methoxymethyl-3-methyl-furo[3,2-g]chromen-7-one | CHEMBL141680
Type:
Small organic molecule
Emp. Form.:
C14H12O4
Mol. Mass.:
244.2427
SMILES:
COCc1cc(=O)oc2cc3occ(C)c3cc12
Structure:
