Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50515559
Substrate
n/a
Meas. Tech.
ChEMBL_1861558 (CHEMBL4362414)
Ki
2.7±n/a nM
Citation
 Tanini, D; Ricci, L; Capperucci, A; Di Cesare Mannelli, L; Ghelardini, C; Peat, TS; Carta, F; Angeli, A; Supuran, CT Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity. Eur J Med Chem 181:0 (2019) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50515559
Synonyms:
CHEMBL4435078
Type:
Small organic molecule
Emp. Form.:
C16H19NO4STe
Mol. Mass.:
449
SMILES:
[#6]-c1ccc([Te;v2][#6]-[#6](-[#8])-[#6]-[#8]-c2ccc(cc2)S([#7])(=O)=O)cc1
Structure:
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