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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50517548
Substrate
n/a
Meas. Tech.
ChEMBL_1869222 (CHEMBL4370288)
IC50
18000±n/a nM
Citation
 Romagnoli, R; Prencipe, F; Oliva, P; Baraldi, S; Baraldi, PG; Schiaffino Ortega, S; Chayah, M; Kimatrai Salvador, M; Lopez-Cara, LC; Brancale, A; Ferla, S; Hamel, E; Ronca, R; Bortolozzi, R; Mariotto, E; Mattiuzzo, E; Viola, G Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors. J Med Chem 62:1274-1290 (2019) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50517548
Synonyms:
CHEMBL4460381
Type:
Small organic molecule
Emp. Form.:
C19H17N3O3S2
Mol. Mass.:
399.487
SMILES:
COc1cc(Nc2ncnc3cc(sc23)-c2cccs2)cc(OC)c1OC
Structure:
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