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Target
Growth hormone secretagogue receptor type 1
Ligand
BDBM50066103
Substrate
n/a
Meas. Tech.
ChEBML_173122
EC50
57±n/a nM
Citation
 Yang, L; Morriello, G; Prendergast, K; Cheng, K; Jacks, T; Chan, WW; Schleim, KD; Smith, RG; Patchett, AA Potent 3-spiropiperidine growth hormone secretagogues. Bioorg Med Chem Lett 8:107-12 (1999) [PubMed]  Article 
Target
Name:
Growth hormone secretagogue receptor type 1
Synonyms:
GH-releasing peptide receptor | GHRP | GHS-R | GHSR_RAT | Ghrelin receptor | Ghsr | Growth hormone secretagogue receptor type 1
Type:
PROTEIN
Mol. Mass.:
40970.19
Organism:
Rattus norvegicus
Description:
ChEMBL_11556
Residue:
364
Sequence:
MWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
  
Inhibitor
Name:
BDBM50066103
Synonyms:
1N-[1-(1H-3-indolylmethyl)-2-oxo-2-[4-oxo-(2'S)-spiro[3H,4H-chromene-2,3'-(hexahydropyridine)]-1-yl]-(1R)-ethyl]-2-amino-2-methylpropanamide | 1N-[1-(1H-3-indolylmethyl)-2-oxo-2-[4-oxo-(2'S)-spiro[4H-chromene-2,3'-(hexahydropyridine)]-1-yl]-(1R)-ethyl]-2-amino-2-methylpropanamide | CHEMBL13926
Type:
Small organic molecule
Emp. Form.:
C28H32N4O4
Mol. Mass.:
488.5781
SMILES:
CC(C)(N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@@]2(C1)CC(=O)c1ccccc1O2
Structure:
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