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Target
Chymotrypsin-like elastase family member 2A
Ligand
BDBM50075116
Substrate
n/a
Meas. Tech.
ChEBML_158076
IC50
2100±n/a nM
Citation
 Iijima, K; Katada, J; Hayashi, Y Symmetrical anhydride-type serine protease inhibitors: structure-activity relationship studies of human chymase inhibitors. Bioorg Med Chem Lett 9:413-8 (1999) [PubMed]  Article 
Target
Name:
Chymotrypsin-like elastase family member 2A
Synonyms:
CEL2A_PIG | CELA2A | ELA2 | ELA2A | Elastase 2A | Elastase-2 | Elastase-2A | Pancreatic elastase
Type:
PROTEIN
Mol. Mass.:
28705.23
Organism:
Sus scrofa
Description:
ChEMBL_156951
Residue:
269
Sequence:
MIRALLLSTLVAGALSCGLPANLPQLPRVVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRHSLSTNEPGSLAVKVSKLVVHQDWNSNQLSNGNDIALLKLASPVSLTDKIQLGCLPAAGTILPNNYVCYVTGWGRLQTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKTNMICAGGDGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSNYIDWINSVIANN
  
Inhibitor
Name:
BDBM50075116
Synonyms:
2-(4-cyanophenylcarboxamido)-1,1-dimethyl-2-(2-methylphenyl)propanoic anhydride | CHEMBL336964
Type:
Small organic molecule
Emp. Form.:
C40H38N4O5
Mol. Mass.:
654.7535
SMILES:
Cc1ccccc1C(NC(=O)c1ccc(cc1)C#N)C(C)(C)C(=O)OC(=O)C(C)(C)C(NC(=O)c1ccc(cc1)C#N)c1ccccc1C
Structure:
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