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Target
D(4) dopamine receptor
Ligand
BDBM50075357
Substrate
n/a
Meas. Tech.
ChEBML_58929
Ki
2±n/a nM
Citation
 Curtis, NR; Kulagowski, JJ; Leeson, PD; Ridgill, MP; Emms, F; Freedman, SB; Patel, S; Patel, S Synthesis and sar of 2- and 3-substituted 7-azaindoles as potential dopamine D4 ligands. Bioorg Med Chem Lett 9:585-8 (1999) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor
Type:
Enzyme
Mol. Mass.:
48373.19
Organism:
Homo sapiens (Human)
Description:
P21917
Residue:
419
Sequence:
MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVATERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCTASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGRDPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSGPGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPGLPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWTPFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
  
Inhibitor
Name:
BDBM50075357
Synonyms:
2-(4-Phenethyl-piperidin-1-ylmethyl)-1H-pyrrolo[2,3-b]pyridine | CHEMBL156732
Type:
Small organic molecule
Emp. Form.:
C21H25N3
Mol. Mass.:
319.4433
SMILES:
C(Cc1ccccc1)C1CCN(Cc2cc3cccnc3[nH]2)CC1
Structure:
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