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Target
Tyrosinase
Ligand
BDBM50521808
Substrate
n/a
Meas. Tech.
ChEMBL_1885378 (CHEMBL4386960)
IC50
25000±n/a nM
Citation
 Santi, MD; Peralta, MA; Puiatti, M; Cabrera, JL; Ortega, MG Melanogenic inhibitory effects of Triangularin in B16F0 melanoma cells, in vitro and molecular docking studies. Bioorg Med Chem 27:3722-3728 (2019) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
TYRO_MOUSE | Tyr
Type:
Protein
Mol. Mass.:
60600.74
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
533
Sequence:
MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
  
Inhibitor
Name:
BDBM50521808
Synonyms:
CHEMBL4462424
Type:
Small organic molecule
Emp. Form.:
C17H16O4
Mol. Mass.:
284.3065
SMILES:
COc1cc(O)c(C(=O)\C=C\c2ccccc2)c(O)c1C
Structure:
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