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Target
Uracil-DNA glycosylase
Ligand
BDBM50078334
Substrate
n/a
Meas. Tech.
ChEMBL_212800 (CHEMBL816908)
IC50
15000±n/a nM
Citation
 Sun, H; Zhi, C; Wright, GE; Ubiali, D; Pregnolato, M; Verri, A; Focher, F; Spadari, S Molecular modeling and synthesis of inhibitors of herpes simplex virus type 1 uracil-DNA glycosylase. J Med Chem 42:2344-50 (1999) [PubMed]  Article 
Target
Name:
Uracil-DNA glycosylase
Synonyms:
DGU | UDG | UNG | UNG1 | UNG15 | UNG_HUMAN | Uracil-DNA glycosylase (UNG)
Type:
Protein
Mol. Mass.:
34661.15
Organism:
Homo sapiens (Human)
Description:
P1305
Residue:
313
Sequence:
MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEESGDAAAIPAKKAPAGQEEPGTPPSSPLSAEQLDRIQRNKAAALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL
  
Inhibitor
Name:
BDBM50078334
Synonyms:
1-(2-Methoxy-ethyl)-6-(4-octyl-phenylamino)-1H-pyrimidine-2,4-dione | CHEMBL305824
Type:
Small organic molecule
Emp. Form.:
C21H31N3O3
Mol. Mass.:
373.4891
SMILES:
CCCCCCCCc1ccc(Nc2cc(=O)[nH]c(=O)n2CCOC)cc1
Structure:
Search PDB for entries with ligand similarity: