Target
Thiosulfate sulfurtransferase
Ligand
BDBM50141532
Substrate
n/a
Meas. Tech.
ChEMBL_1891102 (CHEMBL4392929)
IC50
>100000±n/a nM
Citation
 Stevens, MAbdeen, SSalim, NRay, AMWashburn, AChitre, SSivinski, JPark, YHoang, QQChapman, EJohnson, SM HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules. Bioorg Med Chem Lett 29:1106-1112 (2019) [PubMed]  Article 
Target
Name:
Thiosulfate sulfurtransferase
Synonyms:
2.8.1.1 | Rhodanese | THTR_HUMAN | TST | Thiosulfate sulfurtransferase
Type:
PROTEIN
Mol. Mass.:
33432.06
Organism:
Homo sapiens
Description:
ChEMBL_118080
Residue:
297
Sequence:
MVHQVLYRALVSTKWLAESIRTGKLGPGLRVLDASWYSPGTREARKEYLERHVPGASFFDIEECRDTASPYEMMLPSEAGFAEYVGRLGISNHTHVVVYDGEHLGSFYAPRVWWMFRVFGHRTVSVLNGGFRNWLKEGHPVTSEPSRPEPAVFKATLDRSLLKTYEQVLENLESKRFQLVDSRSQGRFLGTEPEPDAVGLDSGHIRGAVNMPFMDFLTEDGFEKGPEELRALFQTKKVDLSQPLIATCRKGVTACHVALAAYLCGKPDVAVYDGSWSEWFRRAPPESRVSQGKSEKA
  
Inhibitor
Name:
BDBM50141532
Synonyms:
(E)-1-(4-Methoxy-phenyl)-3-phenyl-propenone | 1-(4-Methoxy-phenyl)-3-phenyl-propenone | 1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one (6) | CHEMBL34398 | E)-1-(4-methoxyphenyl)-3-phenylprop-2-en-1-one
Type:
Small organic molecule
Emp. Form.:
C16H14O2
Mol. Mass.:
238.2812
SMILES:
COc1ccc(cc1)C(=O)\C=C\c1ccccc1
Structure:
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