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Target
Dipeptidase 1
Ligand
BDBM50042544
Substrate
n/a
Meas. Tech.
ChEBML_53274
Ki
640000±n/a nM
Citation
 Toney, JH; Cleary, KA; Hammond, GG; Yuan, X; May, WJ; Hutchins, SM; Ashton, WT; Vanderwall, DE Structure-activity relationships of biphenyl tetrazoles as metallo-beta-lactamase inhibitors. Bioorg Med Chem Lett 9:2741-6 (1999) [PubMed]  Article 
Target
Name:
Dipeptidase 1
Synonyms:
DPEP1 | DPEP1_PIG | Dipeptidase 1 | Leukotriene D4 Alpha | Microsomal dipeptidase | RDP | Renal dipeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44697.32
Organism:
GUINEA PIG
Description:
Leukotriene D4 Alpha 0 GUINEA PIG::P22412
Residue:
409
Sequence:
MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSSLAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVTSSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLVDTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYSLCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVGFGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHAQVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
  
Inhibitor
Name:
BDBM50042544
Synonyms:
5-Butyl-2-(2-nitro-phenyl)-4-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2H-pyrazole-3-carboxylic acid | CHEMBL93547
Type:
Small organic molecule
Emp. Form.:
C28H25N7O4
Mol. Mass.:
523.5426
SMILES:
CCCCc1nn(c(C(O)=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)-c1ccccc1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: